Jennifer G. Pearlstein, PhD
Licensed Clinical Psychologist, Writer, Researcher, and Scholar

About Jen
Jennifer Pearlstein, Ph.D. is a licensed clinical psychologist, researcher, and scholar. She operates a private clinical practice and supervises graduate students in the Clinical Science program at Washington University in St. Louis. She received her Ph.D. in Clinical Science from the University of California, Berkeley, and completed her postdoctoral fellowship at the University of Washington in Rehabilitation Medicine. Her work focuses on improving mental healthcare through clinical practice, research, writing, and advocacy.

Clinical Work
Dr. Pearlstein is committed to helping individuals navigate the complex intersection of physical and emotional well-being. Many people come to therapy feeling overwhelmed, stuck, or unsure how to move forward. Her role is to offer a space that is supportive, thoughtful, and grounded in both care and evidence.
She specializes in working with individuals and families navigating chronic illness, chronic pain, and disability. These experiences shape many parts of life—including identity, relationships, work, parenting, and one’s sense of the future—and are frequently misunderstood or minimized. In her work, she focuses on helping people make sense of these realities, develop sustainable coping strategies, and build lives that feel more aligned with what matters most to them.
Dr. Pearlstein provides tailored psychotherapy services that address the unique challenges each person brings to treatment. Her practice emphasizes evidence-based approaches, including Cognitive Behavioral Therapy, Dialectical Behavior Therapy, and Acceptance and Commitment Therapy, and is informed by extensive experience providing individual and group psychotherapy across the lifespan, from adolescents through older adults.
She approaches therapy as a collaborative process grounded in cultural humility and respect for each person’s lived experience. She strives to create a space where clients feel heard, respected, and supported as they work to clarify what is important, understand patterns of coping and distress, and identify changes that feel realistic and meaningful. Her practice affirms diverse identities, including LGBTQ and disabled communities, and is informed by an ongoing commitment to equity and inclusion.
Whether someone is coping with illness or disability, grieving a loss, feeling emotionally stuck, or moving through a difficult season in life, therapy involves slowing down together to understand what is happening and what feels most important. The goal is to support clients in building lives that feel more intentional and workable—strengthening self-trust, resilience, and a sense of possibility.
Dr. Pearlstein aims to inspire hope, resilience, and a renewed sense of possibility in those facing the challenges of chronic pain, illness, disability, and other mental health concerns.
Research
Dr. Pearlstein's program of research has included work on (1) basic mechanisms of psychopathology; (2) treatment development and implementations science, and (3) disability characteristics and mental health outcomes. She is interested in why people struggle under stress and how to intervene to improve mental health outcomes. Ultimately, she strives to use science to identify how to enhance mental health and increase access to care.
Other Interests
Dr. Pearlstein’s work is grounded in values of social justice, equity, and inclusion, with a particular focus on disability, chronic illness, and access to care. Alongside her clinical and academic roles, she writes about the lived experience of disability, parenting, and healthcare systems, with the aim of broadening public understanding of ableism, interdependence, and the everyday realities of navigating inaccessible environments. Her writing appears in her Substack newsletter, Hard Joy, where she explores the emotional, relational, and structural dimensions of disability and care.
Outside of work, Dr. Pearlstein enjoys time with family and friends, good food, being outdoors, and listening to books and podcasts.
